GH stimulation tests: evaluation of GH responses to heat test versus insulin-tolerance test
نویسندگان
چکیده
منابع مشابه
GH stimulation tests: evaluation of GH responses to heat test versus insulin-tolerance test.
OBJECTIVE Heat exposure has been shown to stimulate GH release, but the specificity and the reproducibility have not been determined, and the test has not been compared with validated GH stimulation tests in adulthood. We therefore tested the specificity and the reproducibility of the heat exposure test in healthy subjects and compared the results with those obtained with the insulin-tolerance ...
متن کاملWhich patients do not require a GH stimulation test for the diagnosis of adult GH deficiency?
Adult GH deficiency (GHD) is currently diagnosed in patients with either a history of childhood-onset GHD or acquired hypothalamic-pituitary disease by GH stimulation testing. However, GH stimulation tests are invasive, time consuming, and associated with side effects. Based on preliminary analyses of patients enrolled in the U.S. Hypopituitary Control and Complications Study (HypoCCS), we prop...
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OBJECTIVE The insulin tolerance test (ITT) has been suggested as the gold standard for diagnosing GH deficiency (GHD). The ITT is, however, potentially hazardous. Glucose monitoring during the ITT varies between centres and there is surprisingly little information on the actual level of blood glucose nadir and the duration of hypoglycaemia in patients undergoing the ITT. The aim of the present ...
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OBJECTIVE To identify factors, particularly the growth hormone (GH) provocation test result, affecting growth response to GH treatment in children with GH deficiency (GHD). SUBJECTS A total of 337 prepubertal GHD patients aged <10 years from the UK Pharmacia KIGS database (GH response to provocation test <20 mU/l). OUTCOME MEASURE Annual change in height standard deviation score (SDS) (revi...
متن کاملGH releasing peptide 2 test: the holy grail of testing GH deficiency?
Treatment of growth hormone deficiency (GHD) with GH rests on the accurate biochemical diagnosis of the condition even though clinical symptoms, signs and the assessment of risk factors may aid the diagnosis. This is particularly true for the parallel occurrence of other pituitary dysfunctions, whichmay simplify the procedure according to national and international guidelines (1). Due to the pu...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 1998
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje.0.1390605